sCD14 in Bronchoalveolar Lavage 18, 42 and 162 Hours After Segmental Allergen Provocation
نویسندگان
چکیده
منابع مشابه
Neurotrophins are increased in bronchoalveolar lavage fluid after segmental allergen provocation.
The mechanisms linking inflammation and airway hyperresponsiveness in allergic bronchial asthma are still not completely defined. Since neurotrophic factors increase nerve excitability and neurotransmitter synthesis and are produced by immunocompetent cells, they are likely candidates as mediators of inflammation and hyperresponsiveness. We tested the hypothesis that neurotrophin concentrations...
متن کاملDendritic cell subsets in human bronchoalveolar lavage fluid after segmental allergen challenge.
BACKGROUND Dendritic cells control pulmonary immune reactions. Characteristics of dendritic cells in human bronchoalveolar lavage fluid (BALF) after allergen challenge are unknown. METHODS 7 patients with allergic asthma (median 23 years, range 19-25 years) underwent segmental challenge and were lavaged 10 min and 24 h after challenge. Dendritic cell subsets and surface markers in BALF and in...
متن کاملAIRWAY BIOLOGY Dendritic cell subsets in human bronchoalveolar lavage fluid after segmental allergen challenge
Background: Dendritic cells control pulmonary immune reactions. Characteristics of dendritic cells in human bronchoalveolar lavage fluid (BALF) after allergen challenge are unknown. Methods: 7 patients with allergic asthma (median 23 years, range 19–25 years) underwent segmental challenge and were lavaged 10 min and 24 h after challenge. Dendritic cell subsets and surface markers in BALF and in...
متن کاملCD14 expression and soluble CD14 after segmental allergen provocation in atopic asthma.
Allergic asthma is associated with the recruitment of activated inflammatory cells after allergen challenge. Surface expression of CD14 has been proposed as a marker of cell activation and differentiation. We therefore measured CD14 expression on activated macrophages and granulocytes as well as soluble CD14 (sCD14) concentrations in peripheral blood and bronchoalveolar lavage (BAL) following s...
متن کاملSerial segmental bronchoalveolar lavage in individual rats.
Bronchoalveolar lavage (BAL) is a well-characterized technique for analysis of cellular constituents of the airways and air spaces, but whole lung lavage requires that the animal be euthanized. We describe a technique of segmental BAL in rats that allows serial measurements of inflammation. A tracheal tube was placed, under direct visualization, in lightly anesthetized animals, and a catheter w...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2010
ISSN: 0300-9475,1365-3083
DOI: 10.1111/j.1365-3083.2010.02375.x